8 Common Medications That Can Harm Your Kidneys (And Why Self-Medicating Is Risky)

4. ACE Inhibitors and ARBs (e.g., Lisinopril, Losartan)

These blood pressure medications relax vessels and protect the heart and kidneys in many cases. However, in some situations—like dehydration or significant artery narrowing—they can temporarily reduce filtration rate, leading to elevated creatinine levels.

Regular monitoring helps most people use them safely.

5. Contrast Dyes Used in Imaging Scans (e.g., CT or Angiography Contrast)

Injected dyes help highlight structures in scans but can cause direct toxicity or vasoconstriction in the kidneys, especially in those with reduced function or dehydration.

Hydration before and after procedures often mitigates this risk.

6. Diuretics (e.g., Furosemide, Hydrochlorothiazide)

Known as “water pills,” these remove excess fluid for swelling or high blood pressure. Overuse or use without enough fluids can lead to dehydration, straining kidney function.

Balancing intake and monitoring helps avoid issues.