1. Polypharmacy (Taking 5+ Medications)
The real standout concern: multiple medications interacting.
Studies link polypharmacy to sharply higher adverse events, readmissions, and frailty in heart patients.
Each added pill multiplies complexity—making coordinated review essential.
| Medication Class | Potential Concern in Older Adults | Commonly Suggested Approaches |
|---|---|---|
| Polypharmacy (5+ meds) | Increased interactions, hospitalization risk | Guided deprescribing review |
| NSAIDs | Fluid retention, blood pressure rise | Acetaminophen, physical therapy, topical options |
| Benzodiazepines | Falls, cognitive fog | Sleep hygiene, therapy, shorter alternatives |
| Proton Pump Inhibitors | Nutrient deficiencies, possible CV associations | Lifestyle changes, H2 blockers if appropriate |
| Certain BP/Heart Meds | Electrolyte shifts, low BP | Dose adjustment, regular monitoring |
